Non‑domestic Substances List Amended and Waivers

Summary#

This Canada Gazette notice (published March 28, 2026) records two Environment Department actions under the Canadian Environmental Protection Act, 1999. First, an order removes a small number of chemicals from the Non‑domestic Substances List. Second, the department published a list of companies that were granted waivers so they do not have to provide certain test data when filing New Substances notifications.

What it does#

• Order 2026-87-03-02 Amending the Non-domestic Substances List

  • Deletes the following entries from Part I: 68439-47-4 and 147853-32-5.
  • Deletes the following entry from Part II: 19637-5 (listed as “Phosphorane, pentahalo-, polymer with ammonium halide, P‑carbomono‑cyclicoxy derivs.”).
  • The order comes into force on the same day as Order 2026-87-03-01 Amending the Domestic Substances List (no date given in this notice).

• Waivers of information requirements

  • The Minister (through the department) waived some of the usual testing and information requirements that people must submit when proposing to import or manufacture:
    • living organisms (waivers under subsection 106(8)); and
    • chemical substances (waivers under subsection 81(8)).
  • Types of tests and data waived include things like:
    • tests on effects to aquatic plants, invertebrates and vertebrates;
    • tests on effects to terrestrial plants and invertebrates;
    • antibiotic susceptibility tests and some pathogenicity data;
    • physical‑chemical data such as hydrolysis rate (by pH), octanol/water partition coefficient, vapour pressure, melting/boiling point;
    • biodegradation (ready biodegradation) tests;
    • mutagenicity and repeated‑dose mammalian toxicity tests;
    • molecular weight and residual constituent information.
  • Examples of companies named in the waiver lists include Allogene Therapeutics, AstraZeneca Canada Inc., Gilead Sciences Canada Inc., Novozymes Canada Limited, Sanofi Pasteur Limited, Chevron Oronite Company LLC, and Axalta Coating Systems Canada Company. (The notice lists many more companies with specific waivers.)

Who's affected#

• Companies and organizations that file New Substances notifications with Environment and Health Canada — especially biotechnology, pharmaceutical and chemical firms named in the notice.
• Regulators who review new‑substance filings and who will rely on the reduced datasets for the named cases.
• The item does not identify direct, immediate changes for consumers or the public beyond how new substances and organisms are assessed. If unclear who else is affected, the notice does not say.

Why it matters#

• Removing entries from the Non‑domestic Substances List signals those substances have been moved into the domestic list (the notice says they were added to the Domestic Substances List). That changes which list they appear on and can affect how they are handled under Canada’s New Substances regulatory system.
• Granting waivers means some companies do not have to supply particular test results when seeking permission to import or make new organisms or chemicals. This speeds some filings but also means regulators have less of certain types of test data for those cases.
• These waiver decisions are routine: the notice says about 300 regulatory declarations are submitted each year and about 100 waivers are granted annually. The New Substances program web pages are the place to find more detail.