AAV m-α7-GlyR Added to List

Summary#

Order 2024-112-02-01 Amending the Domestic Substances List (SOR/2024-38) adds a specific living organism to Canada’s inventory of substances. The organism added is Recombinant and non-replicating adeno-associated virus encoding the chimeric ion channel m-α7-GlyR (RP-008). The order was registered and came into force on February 27, 2024.

What it does#

• Adds the named living organism to Part 5 of the Domestic Substances List (the federal inventory of substances on the Canadian market).
• Because it is now on the list, that organism is no longer subject to the New Substances Notification Regulations (Organisms) for new-substance notification.
• The order was signed by Steven Guilbeault (Minister of the Environment) and published as SOR/2024-38.

Who's affected#

• Companies, laboratories or research groups that already make, import or plan to make or import this specific viral construct in Canada.
• Manufacturers or importers who had to follow the New Substances Notification process for this organism — they no longer face that pre-market notification step for this particular organism.
• If it is unclear whether your product or work involves this exact organism, contact Environment Canada (the source gives contact details) to confirm.

Why it matters#

• Being added to the Domestic Substances List means the organism is treated as "not new" to Canada for regulatory notification purposes. That can reduce administrative steps for the entities handling it.
• This change is administrative: it does not mean the government is endorsing the organism, nor does it remove other rules that might apply (for example, biosafety or health regulations).
• For researchers and biotech firms, the change can make it easier to bring that specific material into Canadian labs or supply chains, since one pre-market reporting requirement no longer applies.